Description

tert-Butyl(3-Hydroxyphenethyl)Carbamate is a protected amine derivative, specifically a carbamate, that serves as a versatile and valuable synthetic intermediate in advanced organic chemistry. Its primary value lies in providing a stable, protected amine group that can be selectively deprotected under mild acidic conditions, enabling complex multi-step synthesis. This compound is particularly essential for researchers and manufacturers in the pharmaceutical and agrochemical industries who require high-purity building blocks for developing active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly those targeting neurological and cardiovascular systems.
• Peptide Synthesis: Used in the preparation of peptide analogs where the phenethylamine moiety is required, with the tert-butoxycarbonyl (Boc) group providing amine protection.
• Agrochemical Research: Serves as a precursor in the development of novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Can be utilized in the synthesis of monomers for specialty polymers and advanced functional materials.
• Chemical Biology Probes: Acts as a scaffold for developing molecular probes and inhibitors used in biochemical and cellular studies.

Basic Information

Product Name	tert-Butyl(3-Hydroxyphenethyl)Carbamate
CAS No.	129150-68-1
Molecular Formula	C₁₃H₁₉NO₃
Molecular Weight	237.29 g/mol
Synonyms	Boc-3-Hydroxyphenethylamine; tert-Butyl N-[2-(3-hydroxyphenyl)ethyl]carbamate; 2-(3-Hydroxyphenyl)ethylcarbamic Acid tert-Butyl Ester; N-Boc-3-Hydroxyphenethylamine; N-(tert-Butoxycarbonyl)-3-hydroxyphenethylamine; 3-Hydroxyphenethylamine N-Boc derivative; Carbamic acid, N-[2-(3-hydroxyphenyl)ethyl]-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl(3-Hydroxyphenethyl)Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability, consistency, and reliability for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic; therefore, containers should be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.