Description

Boc-D-4,4'-Biphenylalanine is a protected, non-natural amino acid derivative essential for advanced peptide synthesis. This compound is specifically designed to introduce the rigid, hydrophobic, and aromatic 4,4'-biphenyl moiety into peptide chains, enabling the creation of novel structures with tailored properties. It is a critical building block for researchers and manufacturers in pharmaceutical development, agrochemical research, and materials science who require high-purity, stereochemically defined intermediates.

Application

• Pharmaceutical Research & Development: A key chiral intermediate in the synthesis of peptide-based drug candidates, enzyme inhibitors, and receptor ligands.
• Peptidomimetics Design: Used to incorporate the rigid, planar biphenyl side chain to modulate peptide conformation, stability, and binding affinity.
• Combinatorial Chemistry Libraries: Serves as a valuable building block for creating diverse compound libraries for high-throughput screening.
• Agrochemical Active Ingredients: Employed in the research and synthesis of novel peptides with potential biological activity for crop protection.
• Material Science: Can be utilized in the development of specialty polymers and advanced organic materials requiring specific aromatic functionalities.
• Academic & Institutional Research: Fundamental tool for studying protein-protein interactions, molecular recognition, and structure-activity relationships (SAR).

Basic Information

Product Name	Boc-D-4,4'-Biphenylalanine
CAS No.	128779-47-5
Molecular Formula	C₂₀H₂₃NO₄
Molecular Weight	341.40 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-D-4,4'-biphenylalanine; Boc-D-Biphenylalanine(4,4'); (R)-2-((tert-Butoxycarbonyl)amino)-3-([1,1'-biphenyl]-4-yl)propanoic acid; D-Biphenylalanine(4,4')-Boc; Boc-D-Bip(4,4')-OH; N-Boc-D-4,4'-biphenylalanine; tert-Butyloxycarbonyl-D-4,4'-biphenylalanine; Boc-D-Bph(4,4')-OH
EINECS	Contact for details

Quality Control

Our Boc-D-4,4'-Biphenylalanine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the stringent requirements for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (D-isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.