Description

2-Fluoro-n-(1-Hydroxy-2-Methylpropan-2-Yl)Benzamide is a specialized fluorinated benzamide derivative, serving as a high-value synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both a fluorine atom and a hindered hydroxyalkyl amide group, makes it a critical building block for constructing complex molecules with tailored properties. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the research and synthesis of new drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring fluorinated bioactive molecules.
• Agrochemical Synthesis: Used in developing advanced pesticides and herbicides, where the fluorine atom can enhance biological activity, stability, and metabolic resistance.
• Ligand and Catalyst Development: Serves as a starting material for creating novel ligands in asymmetric catalysis or metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of specialty polymers or advanced organic materials where fluorination modifies physical properties.
• Chemical Biology Probes: Useful for constructing molecular probes to study enzyme function or protein-ligand interactions in biochemical research.

Basic Information

Product Name	2-Fluoro-n-(1-Hydroxy-2-Methylpropan-2-Yl)Benzamide
CAS No.	128764-53-4
Molecular Formula	C11H14FNO2
Molecular Weight	211.23 g/mol
Synonyms	2-Fluoro-N-(2-hydroxy-2-methylpropyl)benzamide; 2-Fluoro-N-(1-hydroxy-2-methylpropan-2-yl)benzamide; 2-Fluoro-N-(2-hydroxy-1,1-dimethylethyl)benzamide; 2-Fluorobenzoic acid (2-hydroxy-1,1-dimethylethyl)amide; 2-Fluoro-N-(2-hydroxy-2-methylpropyl)benzenecarboxamide; Benzamide, 2-fluoro-N-(1-hydroxy-2-methyl-2-propyl)-; 128764-53-4
EINECS	Contact for details

Quality Control

Our 2-Fluoro-n-(1-Hydroxy-2-Methylpropan-2-Yl)Benzamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support custom synthesis and can tailor specifications, including chiral purity if required, to meet specific project needs. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.