Description

2-Deoxy-1,3:4,5-Di-o-Isopropylidene-2-Oxamoylamino-D-Mannitol is a sophisticated chiral building block and protected sugar derivative, essential for advanced organic synthesis. Its primary value lies in its role as a key intermediate for the preparation of complex nucleoside analogs, antiviral agents, and other biologically active compounds. This high-purity intermediate is critically needed by pharmaceutical R&D departments, fine chemical manufacturers, and academic research institutions focused on carbohydrate chemistry and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel nucleoside-based antiviral and anticancer drugs.
• Carbohydrate Chemistry Research: Serves as a protected mannitol derivative for studying glycosylation reactions and synthesizing complex oligosaccharides.
• Chiral Building Block: Utilized in asymmetric synthesis to introduce stereochemical complexity into target molecules.
• Fine Chemical Synthesis: Employed in the production of specialized fine chemicals and advanced materials requiring specific sugar motifs.
• Glycoconjugate Development: Used in the research and development of glycoconjugates for diagnostic and therapeutic applications.
• Academic & Industrial R&D: A valuable reagent for method development and exploratory synthesis in both academic and industrial laboratory settings.

Basic Information

Product Name	2-Deoxy-1,3:4,5-Di-o-Isopropylidene-2-Oxamoylamino-D-Mannitol
CAS No.	128741-75-3
Molecular Formula	C16H26N2O7
Molecular Weight	358.39 g/mol
Synonyms	2-Deoxy-2-[(aminocarbonyl)amino]-1,3:4,5-di-O-(1-methylethylidene)-D-mannitol; 2-Oxamoylamino-2-deoxy-1,3:4,5-di-O-isopropylidene-D-mannitol; D-Mannitol, 2-deoxy-2-[(aminocarbonyl)amino]-, 1,3:4,5-bis-O-(1-methylethylidene)-; Isopropylidene-protected D-Mannitol Oxamoylamino Derivative; Protected Mannitol Oxamate; CAS 128741-75-3
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for high-purity fine chemicals. Each batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity, purity, and chiral integrity. Certificates of Analysis (COA) detailing all relevant specifications are available upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.