Description

Ala-Ser-Thr-Thr-Thr-Asn-3,5-Diiodo-Tyr-Thr is a synthetic, iodinated peptide sequence of significant interest in biochemical research and pharmaceutical development. This compound matters for its role as a key intermediate or reference standard in the study of thyroid hormone analogs, peptide-based radiopharmaceuticals, and metabolic pathways. It is primarily needed by research institutions, pharmaceutical R&D departments, and diagnostic companies focused on endocrinology, targeted drug delivery, and molecular imaging. The product is supplied with a high level of purity and batch-to-batch consistency to meet stringent research and development requirements.

Application

• Pharmaceutical Research & Development: Serves as a critical intermediate or building block in the synthesis of novel peptide-based therapeutics and diagnostic agents.
• Biochemical Reference Standard: Used as a high-purity standard for analytical method development, validation, and quality control in laboratories.
• Endocrinology Studies: Employed in research investigating thyroid hormone metabolism, receptor binding, and the development of hormone analogs.
• Radiopharmaceutical Precursor: Acts as a precursor molecule for the development of iodine-123 or iodine-131 labeled compounds for diagnostic imaging or therapy.
• Peptide Chemistry & Proteomics: Utilized in studies exploring post-translational modifications, peptide stability, and structure-activity relationships (SAR).
• Academic & Institutional Research: Supports fundamental research in biochemistry, molecular biology, and medicinal chemistry at universities and research institutes.

Basic Information

Item	Details
Product Name	Ala-Ser-Thr-Thr-Thr-Asn-3,5-Diiodo-Tyr-Thr
CAS No.	128551-40-6
Molecular Formula	C41H60I2N10O21
Molecular Weight	1299.78 g/mol
Synonyms	ASTTTNDIYT; Alanine-Serine-Threonine-Threonine-Threonine-Asparagine-3,5-Diiodotyrosine-Threonine; H-Ala-Ser-Thr-Thr-Thr-Asn-Tyr(3,5-I2)-Thr-OH; Iodinated Peptide ASTTTNDIYT; 3,5-Diiodo-L-tyrosine-containing octapeptide; L-Alanyl-L-seryl-L-threonyl-L-threonyl-L-threonyl-L-asparaginyl-3,5-diiodo-L-tyrosyl-L-threonine
EINECS	Contact for details

Quality Control

Our Ala-Ser-Thr-Thr-Thr-Asn-3,5-Diiodo-Tyr-Thr is manufactured under controlled conditions to ensure the highest standards of purity and identity. Each batch undergoes rigorous analytical testing, including HPLC for purity and mass spectrometry for confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters to support your quality assurance protocols. Our commitment to cGMP principles and traceability ensures reliable and consistent material for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed in a dry environment. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC-MS)	Conforms
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.