Description

β-Cyclodextrin Methyl Ethers are chemically modified cyclodextrins where hydroxyl groups are substituted with methyl groups, enhancing their solubility and altering their inclusion complexation properties. This modification is critical for improving the stability, bioavailability, and delivery of active ingredients in demanding formulations. It is an essential functional excipient and solubilizing agent for the pharmaceutical, food, and cosmetic industries, where precise molecular encapsulation is required.

Application

• Pharmaceutical Formulations: As a solubility enhancer and stabilizer for poorly water-soluble active pharmaceutical ingredients (APIs), improving drug delivery and bioavailability.
• Food & Flavor Industry: For the encapsulation and protection of sensitive flavors, colors, and nutrients, masking off-tastes and controlling release.
• Cosmetics & Personal Care: To stabilize fragrances, vitamins, and other active compounds in creams, lotions, and serums, enhancing product shelf-life and efficacy.
• Chemical Analysis & Separation: Employed as a chiral stationary phase modifier in chromatography for the separation of enantiomers.
• Agrochemicals: For the encapsulation of pesticides or herbicides to control their release rate and reduce environmental impact.
• Research & Development: Used as a tool in supramolecular chemistry and material science for constructing host-guest complexes and functional materials.

Basic Information

Product Name	β-Cyclodextrin Methyl Ethers
CAS No.	128446-36-6
Molecular Formula	Typically C56H98O35 (for a specific degree of substitution; varies)
Molecular Weight	Variable based on degree of methylation (DS). Contact for details.
Synonyms	Methyl-β-Cyclodextrin; Methyl Beta Cyclodextrin; Heptakis(2,6-di-O-methyl)-β-cyclodextrin; Randomly Methylated-β-Cyclodextrin (RM-β-CD); β-Cyclodextrin, methyl ethers; M-β-CD; Dimethyl-β-cyclodextrin; 2,6-Di-O-methyl-β-cyclodextrin
EINECS	Contact for details.

Quality Control

Our β-Cyclodextrin Methyl Ethers are manufactured under a strict quality management system. Each batch is tested to ensure it meets stringent specifications for identity, purity, and performance. Certificates of Analysis (COA) documenting key parameters such as degree of substitution, residual solvents, and heavy metals are provided with every shipment. We support compliance with relevant guidelines for pharmaceutical (ICH Q3), food (FCC), and cosmetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed after opening to prevent absorption of atmospheric moisture, which can affect performance.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Degree of Substitution (DS)	10.0 - 14.0 (or as specified)
Water Content (KF)	≤ 5.0 %
Residue on Ignition	≤ 0.1 %
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH limits
Microbial Limits	Meets Ph. Eur./USP criteria

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.