Description

Chromosorb P/HMDS is a high-performance, surface-modified chromatographic support material designed for superior inertness and peak shape in gas chromatography. Its core value lies in providing a reliable, non-polar stationary phase for the precise separation of challenging compounds, particularly amines and other polar analytes. This product is essential for analytical laboratories and quality control departments in the pharmaceutical, environmental, petrochemical, and food & beverage industries requiring robust and reproducible GC analyses.

Application

• Gas Chromatography (GC) as a deactivated, non-polar solid support for packed columns.
• Separation of amines, pharmaceuticals, and other basic or polar compounds that may tail on untreated supports.
• Analysis of volatile organic compounds (VOCs) in environmental testing and air quality monitoring.
• Quality control and purity assessment in pharmaceutical synthesis and manufacturing.
• Petrochemical analysis, including the separation of hydrocarbon mixtures.
• Food and flavor analysis where inert column surfaces are critical for accurate component identification.
• Research and development in academic and industrial chemical laboratories.
• As a specialized support material for preparing custom-packed GC columns with specific selectivity.

Basic Information

Product Name	Chromosorb P/HMDS
CAS No.	12623-98-2
Molecular Formula	N/A (Modified Diatomaceous Earth)
Molecular Weight	N/A
Synonyms	Chromosorb P HMDS; HMDS-treated Chromosorb P; Hexamethyldisilazane-treated Chromosorb P; Silanized Chromosorb P; Gas Chrom P HMDS; Deactivated Chromosorb P; Non-polar GC support; Diatomaceous earth, calcined, silanized; Chromatographic support, HMDS-treated
EINECS	Contact for details

Quality Control

Our Chromosorb P/HMDS is manufactured under strict quality protocols to ensure batch-to-batch consistency and performance reliability for critical chromatographic applications. Each lot undergoes rigorous testing for key parameters such as mesh size, surface activity, and deactivation efficiency. A Certificate of Analysis (COA) detailing these specifications is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed when not in use to prevent adsorption of atmospheric moisture, which can affect chromatographic performance.

Specification

Item	Specification
Appearance	White to off-white powder
Mesh Size	60/80, 80/100, or 100/120 (Custom sizes available)
Surface Treatment	Hexamethyldisilazane (HMDS)
Inertness Test (for basic compounds)	Pass
Maximum Operating Temperature	Contact for details
Loss on Drying	< 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.