Description

Alanine, n-(3-Fluoro-2-Hydroxybenzoyl)-2-Methyl- is a specialized fluorinated benzoyl alanine derivative, a high-value building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique fluorine-substituted aromatic structure imparts desirable biological activity and metabolic stability. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to innovate new molecular entities.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibition or receptor modulation.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atom enhances lipophilicity and biological efficacy.
• Peptidomimetic Synthesis: Serves as a non-natural amino acid derivative for constructing peptide analogs with improved stability and pharmacological profiles.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and protein functions.
• Fine Chemical Production: Acts as a specialized intermediate for custom synthesis and contract manufacturing of complex organic molecules.
• Material Science Research: Potential precursor for advanced organic materials and ligands in catalytic systems.

Basic Information

Item	Details
Product Name	Alanine, n-(3-Fluoro-2-Hydroxybenzoyl)-2-Methyl-
CAS No.	128396-75-8
Molecular Formula	C11H12FNO3
Molecular Weight	225.22 g/mol
Synonyms	2-Methyl-N-(3-fluoro-2-hydroxybenzoyl)alanine; N-(3-Fluoro-2-hydroxybenzoyl)-2-methylalanine; 3-Fluoro-2-hydroxy-N-(1-carboxyethyl)benzamide; Alanine, N-(3-fluoro-2-hydroxybenzoyl)-2-methyl-; (2R)-2-[(3-Fluoro-2-hydroxybenzoyl)amino]propanoic acid (for specific enantiomer); 3-Fluoro-2-hydroxybenzoyl-2-methylalanine; Fluorohydroxybenzoyl alanine derivative
EINECS	Contact for details

Quality Control

Our Alanine, n-(3-Fluoro-2-Hydroxybenzoyl)-2-Methyl- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and spectroscopic identification (NMR, IR, MS), to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound may be sensitive to strong bases and fluorides; keep away from incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.