Description

n-Bromoacetylleucylglycine is a specialized peptide derivative designed for advanced chemical synthesis and biochemical research. This compound serves as a crucial building block for the development of enzyme inhibitors and active pharmaceutical ingredients (APIs), offering precise reactivity for targeted molecular modifications. It is primarily utilized by research institutions and pharmaceutical companies engaged in peptide chemistry, medicinal chemistry, and proteomics studies.

Application

• Peptide Synthesis Intermediate: A key reagent for the site-specific modification and elongation of peptide chains.
• Enzyme Inhibitor Development: Used in the research and synthesis of potent, irreversible inhibitors for serine and cysteine proteases.
• Pharmaceutical Research: Serves as a critical precursor in the development of novel therapeutic agents and active pharmaceutical ingredients (APIs).
• Bioconjugation: Employed for labeling peptides and proteins with functional groups for diagnostic or targeting purposes.
• Chemical Biology Probes: Utilized to create activity-based probes for studying enzyme function and mechanism in complex biological systems.
• Academic & Industrial R&D: A valuable tool for universities and contract research organizations (CROs) exploring new chemical entities and biochemical pathways.

Basic Information

Product Name	n-Bromoacetylleucylglycine
CAS No.	128395-64-2
Molecular Formula	C₁₀H₁₇BrN₂O₄
Molecular Weight	309.16 g/mol
Synonyms	Bromoacetyl-Leu-Gly-OH; N-Bromoacetyl-L-leucylglycine; L-Leucine, N-(bromoacetyl)-, glycyl-; Ac-Leu-Gly-Br; Bromoacetyl-leucyl-glycine; Bz-Leu-Gly; (2S)-2-[(2-Bromoacetyl)amino]-4-methyl-N-(2-oxo-2-{[2-(2-oxoethyl)amino]ethyl}amino)pentanamide
EINECS	Contact for details

Quality Control

Our n-Bromoacetylleucylglycine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.