Description

Borane-Di(tert-Butyl)Phosphine Complex is a versatile organophosphorus reagent where a borane (BH₃) moiety is coordinated to a sterically hindered di(tert-butyl)phosphine ligand. This complex is valued for its role as a stable, air-sensitive precursor to highly nucleophilic tertiary phosphines, which are crucial catalysts and ligands in modern synthetic chemistry. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for applications in cross-coupling, hydrofunctionalization, and other transition metal-catalyzed reactions.

Application

• Catalyst/Ligand Precursor: In situ generation of the highly active di(tert-butyl)phosphine ligand for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Buchwald-Hartwig amination).
• Pharmaceutical Intermediate Synthesis: Used in the synthesis of complex drug molecules where robust and selective catalysis is required.
• Agrochemical Research: Employed in the development of novel pesticides and herbicides through catalytic C-X bond formation.
• Polymer Chemistry: Acts as a catalyst component in the polymerization of specialty monomers and the synthesis of functional polymers.
• Hydrofunctionalization Reactions: Serves as a precursor to phosphine catalysts for hydroboration, hydrosilylation, and hydrogenation of alkenes and alkynes.
• Material Science: Used in the surface functionalization of nanoparticles and the creation of phosphine-based ligands for novel metal-organic frameworks (MOFs).
• Academic & Industrial R&D: A key reagent for methodological development in organic and organometallic chemistry laboratories.

Basic Information

Product Name	Borane-Di(tert-Butyl)Phosphine Complex
CAS No.	128363-76-8
Molecular Formula	C₈H₂₂BP
Molecular Weight	160.06 g/mol
Synonyms	Di-tert-butylphosphine borane complex; (tert-Bu)₂PH•BH₃; Di-tert-butylphosphine-borane; Borane-tert-butylphosphine complex; Borane - di-tert-butylphosphine (1:1); Di(tert-butyl)phosphine borane adduct; DTBP•BH₃; P,P-Di-tert-butylphosphinous acid borane complex
EINECS	Contact for details

Quality Control

Our Borane-Di(tert-Butyl)Phosphine Complex is manufactured under strict quality protocols. Each batch undergoes rigorous analytical testing, including NMR (¹H, ¹¹B, ³¹P) and HPLC analysis, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing batch-specific results are available upon request. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a cool, dry, and well-ventilated place. Due to its sensitivity to oxidation and moisture, containers should be kept sealed and allowed to reach room temperature before opening to minimize condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
¹H NMR Assay	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.