Description

Carbamic Acid, [(4R)-3-Oxo-4-Isoxazolidinyl]-, 1,1-Dimethylethyl Ester (9Ci) is a high-purity, chiral chemical intermediate of significant importance in advanced organic synthesis. This compound is valued for its role as a key building block in the development of complex, biologically active molecules, particularly within the pharmaceutical sector. It is primarily sought after by research institutions and manufacturers engaged in the synthesis of novel therapeutics, agrochemicals, and other fine chemicals where stereochemical control is critical.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially in classes like β-lactam antibiotics and enzyme inhibitors.
• Agrochemical Synthesis: Used in the production of advanced, stereospecific pesticides and herbicides where the specific (4R) configuration can influence biological activity.
• Organic Synthesis Building Block: Serves as a protected amino acid derivative or a chiral isoxazolidinone scaffold for constructing complex molecular architectures in academic and industrial R&D.
• Process Chemistry: Employed in scale-up and pilot plant studies for the manufacture of optically pure compounds, benefiting from its defined stereochemistry.
• Bioconjugation & Probe Development: Potential use in the synthesis of molecular probes and bioconjugates for biochemical and diagnostic applications due to its reactive ester functionality.

Basic Information

Product Name	Carbamic Acid, [(4R)-3-Oxo-4-Isoxazolidinyl]-, 1,1-Dimethylethyl Ester (9Ci)
CAS No.	128346-20-3
Molecular Formula	C8H14N2O4
Molecular Weight	202.21 g/mol
Synonyms	(4R)-3-Oxo-4-isoxazolidinecarboxylic acid tert-butyl ester; tert-Butyl (4R)-3-oxo-1,2-oxazolidine-4-carboxylate; (R)-tert-Butyl 3-oxoisoxazolidine-4-carboxylate; (R)-3-Oxoisoxazolidine-4-carboxylic acid tert-butyl ester; (4R)-tert-Butoxycarbonyl-3-isoxazolidinone; BOC-(R)-3-Oxoisoxazolidine-4-carboxylic acid; (R)-N-Boc-3-isoxazolidinone-4-carboxylic acid; 128346-20-3
EINECS	Contact for details

Quality Control

Our Carbamic Acid, [(4R)-3-Oxo-4-Isoxazolidinyl]-, 1,1-Dimethylethyl Ester (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.