Description

Hla-Drb1 CAS NO 128338-86-3 is a high-purity synthetic peptide sequence corresponding to a specific epitope of the human leukocyte antigen (HLA) class II histocompatibility antigen, DRB1 chain. This compound is a critical reagent for immunological research, diagnostics, and therapeutic development, enabling precise study of antigen presentation and T-cell mediated immune responses. It is primarily utilized by biotechnology firms, academic research institutions, and pharmaceutical companies engaged in autoimmune disease research, vaccine development, and personalized medicine.

Application

• Immunological Research: Used as a defined antigen in studies of T-cell receptor binding, epitope mapping, and immune response mechanisms.
• Diagnostic Assay Development: Serves as a key component in the development of ELISA, ELISpot, and other immunoassays for detecting specific HLA-DRB1 associated antibodies or T-cell reactivity.
• Autoimmune Disease Studies: Essential for investigating the role of specific HLA-DRB1 alleles in diseases like rheumatoid arthritis, type 1 diabetes, and multiple sclerosis.
• Vaccine Research: Employed in the design and testing of peptide-based vaccines to modulate immune responses.
• Quality Control & Standardization: Acts as a reference standard for lot-to-lay consistency in the production of related biological reagents and diagnostic kits.
• Therapeutic Peptide Screening: Used in high-throughput screening platforms to identify potential therapeutic peptides or inhibitors that interact with the HLA-DRB1 molecule.

Basic Information

Product Name	Hla-Drb1
CAS No.	128338-86-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	HLA-DRB1 Peptide; HLA Class II Histocompatibility Antigen, DRB1 Chain; DRB1 Epitope; MHC Class II Antigen DRB1; Human Leukocyte Antigen DRB1 Peptide; HLA-DRB1* Epitope; Synthetic HLA-DRB1 Antigen
EINECS	Contact for details

Quality Control

Our Hla-Drb1 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity verification and mass spectrometry (MS) for identity confirmation, to ensure it meets the exacting standards required for research and diagnostic applications. Certificates of Analysis (COA) detailing purity, peptide content, and analytical results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, consider aliquoting to minimize freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (Mass Spec)	Conforms
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Solubility	Soluble in water or appropriate aqueous buffer
Single-Letter Sequence	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.