Description

3-(n-Boc-Methylamino)Propionitrile is a versatile and high-purity chemical building block, specifically a Boc-protected amino nitrile derivative. This compound is essential for the efficient synthesis of complex molecules, offering a protected amine group that is crucial for multi-step organic transformations. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing peptide mimetics, active pharmaceutical ingredients (APIs), and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), particularly those requiring protected amine functionalities.
• Peptidomimetic Chemistry: Serves as a crucial building block for creating non-peptide compounds that mimic the structure and function of peptides, important in drug discovery.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides where specific amine-protected intermediates are required.
• Custom Chemical Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects and scale-up processes.
• Academic & Industrial R&D: A valuable reagent in research laboratories for methodological development in organic synthesis and medicinal chemistry.
• Ligand and Catalyst Preparation: Can be utilized in the synthesis of specialized ligands and catalysts for asymmetric synthesis and other catalytic applications.

Basic Information

Product Name	3-(n-Boc-Methylamino)Propionitrile
CAS No.	128304-84-7
Molecular Formula	C9H16N2O2
Molecular Weight	184.24 g/mol
Synonyms	tert-Butyl (2-Cyanoethyl)(methyl)carbamate; 3-[(tert-Butoxycarbonyl)(methyl)amino]propanenitrile; N-Boc-N-Methyl-β-alanine Nitrile; Boc-N-Me-β-Ala-CN; (2-Cyanoethyl)methylcarbamic Acid tert-Butyl Ester; 3-[(Methyl)(Boc)amino]propionitrile; 3-(N-Boc-N-Methylamino)propionitrile; N-Methyl-N-(2-cyanoethyl)carbamic Acid tert-Butyl Ester
EINECS	Contact for details

Quality Control

Our 3-(n-Boc-Methylamino)Propionitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and commercial synthesis. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to minimize exposure to atmospheric moisture. Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.