Description

1-Pyrrolidinecarboxamide,n-Hydroxy-2-(Hydroxymethyl)-,(S)-(9Ci) is a high-purity chiral compound of significant interest in advanced organic synthesis. This specialized chemical serves as a critical building block and intermediate for the development of novel pharmaceutical agents and bioactive molecules. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for applications requiring precise stereochemistry and functional group manipulation.

Application

• Pharmaceutical Intermediate: Key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for neurological and metabolic disorders.
• Protease Inhibitor Synthesis: Used in the construction of complex molecular scaffolds targeting various protease enzymes.
• Agrochemical Research: Serves as a precursor in the synthesis of novel, enantiomerically pure herbicides and pesticides.
• Bioconjugation & Linker Chemistry: Utilized in the development of antibody-drug conjugates (ADCs) and other targeted therapeutic platforms due to its functional handles.
• Catalyst & Ligand Development: Acts as a precursor for chiral ligands used in asymmetric catalysis.
• Academic & Industrial R&D: Employed in methodological studies and process chemistry for route scouting and optimization.

Basic Information

Product Name	1-Pyrrolidinecarboxamide,n-Hydroxy-2-(Hydroxymethyl)-,(S)-(9Ci)
CAS No.	128252-45-9
Molecular Formula	C6H12N2O3
Molecular Weight	160.17 g/mol
Synonyms	(S)-2-(Hydroxymethyl)-N-hydroxypyrrolidine-1-carboxamide; (S)-N-Hydroxy-2-(hydroxymethyl)pyrrolidine-1-carboxamide; (2S)-2-(Hydroxymethyl)-N-hydroxypyrrolidine-1-carboxamide; L-N-Hydroxy-2-(hydroxymethyl)pyrrolidine-1-carboxamide; Hydroxamate derivative of L-prolinol; (S)-Pyrrolidine-1-carboxylic acid hydroxyamide derivative; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 1-Pyrrolidinecarboxamide,n-Hydroxy-2-(Hydroxymethyl)-,(S)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and cGMP manufacturing. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.