Description

7-(2-(2-Aminothiazole-4-Yl)-2-(1-Carboxy-1-Methyl)Ethoxyiminoacetamido)-3-(3-Hydroxy-4-Pyridon-1-Yl)Methyl-3-Cephem-4-Carboxylic Acid is a high-purity advanced pharmaceutical intermediate, specifically a cephalosporin nucleus derivative. This compound is critical for the synthesis of next-generation, broad-spectrum cephalosporin antibiotics, offering a key building block for enhanced efficacy and stability. It is primarily required by pharmaceutical manufacturers and R&D facilities engaged in the development and production of advanced β-lactam antibiotics.

Application

• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a crucial intermediate in the multi-step synthesis of advanced cephalosporin antibiotics.
• Pharmaceutical Research & Development: Used in medicinal chemistry for the design and development of new antibiotic candidates with improved pharmacokinetic profiles.
• Process Chemistry & Scale-Up: Employed in process optimization and pilot-scale manufacturing of cephalosporin-based drugs.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and regulatory testing of finished pharmaceutical products.

Basic Information

Product Name	7-(2-(2-Aminothiazole-4-Yl)-2-(1-Carboxy-1-Methyl)Ethoxyiminoacetamido)-3-(3-Hydroxy-4-Pyridon-1-Yl)Methyl-3-Cephem-4-Carboxylic Acid
CAS No.	128236-34-0
Molecular Formula	C22H22N6O8S2
Molecular Weight	562.57 g/mol
Synonyms	(6R,7R)-7-[(Z)-2-(2-Aminothiazol-4-yl)-2-(1-carboxy-1-methoxyimino)acetamido]-3-(3-hydroxy-4-pyridinio)methyl-3-cephem-4-carboxylate; Cephalosporin C-7 Side Chain Intermediate; 7-ACA Derivative; 7-ATCA; (Z)-7-(2-(2-Aminothiazol-4-yl)-2-(1-carboxy-1-methoxyimino)acetamido)-3-(3-hydroxy-4-pyridinio)methyl-3-cephem-4-carboxylic acid; Cefepime Intermediate; Cephalosporin Nucleus Ester
EINECS	Contact for details

Quality Control

Our 7-(2-(2-Aminothiazole-4-Yl)-2-(1-Carboxy-1-Methyl)Ethoxyiminoacetamido)-3-(3-Hydroxy-4-Pyridon-1-Yl)Methyl-3-Cephem-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure compliance with pharmaceutical intermediate standards. Comprehensive Certificates of Analysis (COA) detailing all test results are provided to guarantee traceability and support your regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed in a desiccated environment and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.