Description

Methyl 4-Bromohexafluorobutanoate is a high-value fluorinated building block and reagent essential for advanced organic synthesis. Its core value proposition lies in introducing both a reactive bromine atom and a stable, lipophilic hexafluorobutyl segment into target molecules, enabling the development of compounds with enhanced properties. This product is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty materials sectors for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing fluorinated active pharmaceutical ingredients (APIs), where the fluorine atoms can improve metabolic stability, bioavailability, and membrane permeability.
• Agrochemical Synthesis: Used in the research and production of advanced fluorinated pesticides and herbicides, leveraging the fluorine's ability to enhance biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, where the hexafluorobutyl group can influence dielectric anisotropy and thermal stability.
• Polymer Modification: Employed to incorporate fluorinated side chains into polymers, imparting valuable characteristics such as oil/water repellency, chemical resistance, and low surface energy.
• Cross-Coupling Reactions: The bromine atom makes it a suitable substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Negishi) to form carbon-carbon bonds.
• Nucleophilic Substitution: The ester and bromide functionalities allow for sequential derivatization, enabling the construction of complex molecular architectures.

Basic Information

Item	Details
Product Name	Methyl 4-Bromohexafluorobutanoate
CAS No.	128160-31-6
Molecular Formula	C5H3BrF6O2
Molecular Weight	264.97 g/mol
Synonyms	4-Bromohexafluorobutanoic Acid Methyl Ester; Methyl 4-Bromoperfluorobutanoate; Methyl 4-Bromo-2,2,3,3,4,4-hexafluorobutanoate; 4-Bromo-2,2,3,3,4,4-hexafluorobutanoic Acid Methyl Ester; Perfluorobutanoic Acid, 4-Bromo-, Methyl Ester; Methyl α,α,β,β,γ,γ-Hexafluoro-γ-bromobutyrate
EINECS	Contact for details

Quality Control

Our Methyl 4-Bromohexafluorobutanoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports your cGMP and ISO 9001 compliance needs for traceability and reliability in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong alkalis and sources of ignition. Due to the presence of fluoride and bromine, handle with appropriate personal protective equipment in a fume hood.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.