Description

Cyclohexanecarboxylic Acid, 4-(2,2,2-Trifluoroethoxy)-, Trans is a high-value, fluorinated organic building block characterized by its trans-configured cyclohexane ring and trifluoroethoxy side chain. This compound is essential for introducing specific steric and electronic properties into advanced molecular architectures, enabling the development of novel materials and active ingredients. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for use in medicinal chemistry and crop protection science.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders or metabolic diseases.
• Agrochemical Synthesis: Serves as a critical precursor in the design and synthesis of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & Advanced Material Research: Used in the development of fluorinated liquid crystals and specialty polymers, where its rigid, fluorinated structure contributes to desired optical and thermal properties.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex, stereodefined molecules, leveraging its carboxylic acid functionality for further derivatization.
• Flavor & Fragrance Chemistry: Potential use in the synthesis of novel, high-value aroma chemicals, where the trifluoroethoxy group can impart unique organoleptic characteristics.

Basic Information

Product Name	Cyclohexanecarboxylic Acid, 4-(2,2,2-Trifluoroethoxy)-, Trans
CAS No.	128140-49-8
Molecular Formula	C9H13F3O3
Molecular Weight	226.19 g/mol
Synonyms	trans-4-(2,2,2-Trifluoroethoxy)cyclohexanecarboxylic Acid; (1r,4r)-4-(2,2,2-Trifluoroethoxy)cyclohexane-1-carboxylic Acid; 4-(2,2,2-Trifluoroethoxy)cyclohexanecarboxylic Acid (trans); 4-(Trifluoroethoxy)cyclohexanecarboxylic Acid; Cyclohexanecarboxylic acid, 4-(2,2,2-trifluoroethoxy)-, (1R,4R)-rel-; 128140-49-8; 4-(2,2,2-Trifluoroethoxy)-trans-cyclohexanecarboxylic Acid
EINECS	Contact for details

Quality Control

Our production of Cyclohexanecarboxylic Acid, 4-(2,2,2-Trifluoroethoxy)-, Trans adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the exacting standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and fluorides. For long-term storage, consider inert gas purging to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% trans-isomer
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.