Description

1-(Benzyloxy)-3-Ethynylbenzene is a specialized aromatic ether building block featuring both a benzyl-protected phenol and a terminal alkyne functional group. This unique bifunctional structure makes it a valuable intermediate for advanced organic synthesis, particularly in the construction of complex molecular architectures. It is primarily utilized by research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors for applications such as click chemistry, cross-coupling reactions, and polymer synthesis.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs) via Sonogashira coupling and other metal-catalyzed reactions.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and plant growth regulators.
• Click Chemistry: The terminal alkyne group enables efficient Huisgen 1,3-dipolar cycloaddition (copper-catalyzed azide-alkyne cycloaddition) for bioconjugation and material science.
• Liquid Crystal & OLED Materials: Serves as a building block for creating conjugated organic molecules used in electronic displays and optoelectronic devices.
• Polymer Chemistry: A monomer for synthesizing specialty polymers with tailored thermal, mechanical, or optical properties.
• Chemical Research: A versatile reagent in academic and industrial R&D for exploring new synthetic methodologies and creating molecular libraries.

Basic Information

Product Name	1-(Benzyloxy)-3-Ethynylbenzene
CAS No.	128133-59-5
Molecular Formula	C15H12O
Molecular Weight	208.26 g/mol
Synonyms	3-(Benzyloxy)phenylacetylene; 3-Ethynylphenyl benzyl ether; m-(Benzyloxy)phenylacetylene; 1-Ethynyl-3-(phenylmethoxy)benzene; Benzyl 3-ethynylphenyl ether; 3-Benzyloxyphenylacetylene
EINECS	Contact for details

Quality Control

Our production of 1-(Benzyloxy)-3-Ethynylbenzene adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including GC, HPLC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.