Description

(S)-(-)-Alpha,α-Di(2-Naphthyl)-2-Pyrrolidinemethanol is a high-value, enantiomerically pure chiral ligand and catalyst precursor. This compound matters for its critical role in facilitating asymmetric synthesis, enabling the production of single-isomer pharmaceutical intermediates and fine chemicals with high stereoselectivity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity chiral auxiliaries.

Application

• Asymmetric Catalysis: As a chiral ligand for transition metal-catalyzed reactions, including additions and cross-couplings.
• Pharmaceutical Intermediate Synthesis: Key building block in the production of enantiomerically pure active pharmaceutical ingredients (APIs).
• Chiral Resolution Agent: Used to separate racemic mixtures of acids, alcohols, or amines via diastereomeric salt formation.
• Organocatalysis: Employed as a catalyst or catalyst precursor in enantioselective organic transformations.
• Agrochemical Research: For developing chiral pesticides and herbicides with improved efficacy and environmental profiles.
• Material Science: In the synthesis of chiral polymers or liquid crystals for advanced optical applications.

Basic Information

Product Name	(S)-(-)-Alpha,α-Di(2-Naphthyl)-2-Pyrrolidinemethanol
CAS No.	127986-84-9
Molecular Formula	C25H23NO
Molecular Weight	353.46 g/mol
Synonyms	(S)-(-)-α,α-Bis(2-naphthyl)-2-pyrrolidinemethanol; (S)-(-)-2-(Di-2-naphthylhydroxymethyl)pyrrolidine; (S)-(-)-Di(2-naphthyl)prolinol; (S)-(-)-DBNP; (S)-ProNol; (S)-(-)-α,α-Di-2-naphthyl-2-pyrrolidinemethanol; (S)-(-)-Di(2-naphthyl)pyrrolidinemethanol
EINECS	Contact for details

Quality Control

Our (S)-(-)-Alpha,α-Di(2-Naphthyl)-2-Pyrrolidinemethanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.