Description

2-(Trifluoromethoxy)Benzamide is a high-purity, fluorinated aromatic building block of significant interest in advanced organic synthesis. Its core value lies in the unique properties imparted by the trifluoromethoxy group, which is prized for enhancing metabolic stability, lipophilicity, and bioavailability in target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in areas requiring fluorinated motifs for improved pharmacokinetics.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides where the trifluoromethoxy group can contribute to biological activity and environmental stability.
• Material Science Precursor: Serves as a building block for specialty polymers and liquid crystals that benefit from fluorine-containing aromatic units.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, amide bond formations, and other transformations to introduce the 2-(trifluoromethoxy)benzoyl moiety.
• Chemical Biology Probe Development: Utilized in the design of molecular probes and inhibitors for studying enzyme function and biological pathways.

Basic Information

Product Name	2-(Trifluoromethoxy)Benzamide
CAS No.	127979-74-2
Molecular Formula	C8H6F3NO2
Molecular Weight	205.14 g/mol
Synonyms	2-(Trifluoromethoxy)benzamide; o-(Trifluoromethoxy)benzamide; Benzamide, 2-(trifluoromethoxy)-; α,α,α-Trifluoro-o-anisamide; 2-Trifluoromethoxybenzoic acid amide
EINECS	Contact for details

Quality Control

Our 2-(Trifluoromethoxy)Benzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.