Description

Murine Cmv Pp 89 (168-176) is a synthetic peptide fragment corresponding to residues 168-176 of the murine cytomegalovirus (MCMV) phosphoprotein 89 (pp89). This high-purity peptide is a critical research-grade biochemical tool for immunology and virology studies. It is primarily utilized by researchers in pharmaceutical R&D and academic institutions investigating T-cell-mediated immune responses, antigen presentation, and vaccine development against cytomegalovirus infections.

Application

• Immunological Research: Used as a defined antigen to study CD8+ T-cell responses and epitope mapping in murine models of CMV infection.
• Vaccine Development: Serves as a reference standard or a component in preclinical studies for evaluating novel CMV vaccine candidates and adjuvants.
• T-Cell Assay Standard: Acts as a positive control or stimulation agent in ELISPOT, intracellular cytokine staining (ICS), and tetramer staining assays to monitor antigen-specific cytotoxic T lymphocytes (CTLs).
• Mechanistic Studies: Employed in research focused on MHC class I (H-2Ld) binding and antigen processing pathways.
• Reagent Production: Used in the generation and validation of monoclonal antibodies or T-cell receptor (TCR) transgenic models specific for this immunodominant epitope.

Basic Information

Product Name	Murine Cmv Pp 89 (168-176)
CAS No.	127902-44-7
Molecular Formula	C50H78N14O13
Molecular Weight	1083.2 g/mol
Synonyms	MCMV pp89 (168-176); pp89168-176; H-2Ld-restricted MCMV epitope; YPHFMPTNL peptide; Cytomegalovirus phosphoprotein 89 peptide (168-176); Murine CMV immediate-early protein 1 peptide; IE1168-176; Antigenic peptide YPHFMPTNL
EINECS	Contact for details

Quality Control

Our Murine Cmv Pp 89 (168-176) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and MS for identity confirmation, to ensure it meets the high standards required for critical research applications. Certificates of Analysis (COA) detailing purity, amino acid analysis, and other relevant specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term storage, keep the lyophilized powder at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption. Reconstituted solutions should be aliquoted and stored at ≤ -20°C; avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Amino Acid Composition	Conforms to theoretical values
Peptide Content	≥ 70% (by weight)
Solubility	Soluble in water or dilute aqueous acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.