Description

(-)-Mod-Diop CAS NO 127797-02-8 is a high-purity chiral ligand and organocatalyst, specifically the (-)-enantiomer of a modified diop derivative. This compound is critical for enabling highly stereoselective transformations in asymmetric synthesis, offering researchers and manufacturers precise control over the three-dimensional structure of complex molecules. It is an essential tool for advanced R&D and production in the pharmaceutical, agrochemical, and fine chemical industries, where creating single-enantiomer products is paramount for efficacy and safety.

Application

• As a chiral ligand in asymmetric hydrogenation and other transition metal-catalyzed reactions.
• As an organocatalyst for enantioselective carbon-carbon and carbon-heteroatom bond-forming reactions.
• Key intermediate in the research and development of novel active pharmaceutical ingredients (APIs).
• Use in the synthesis of enantiomerically pure agrochemicals and specialty chemicals.
• Tool compound for methodological development in academic and industrial organic chemistry laboratories.
• Component in catalyst screening kits for high-throughput experimentation (HTE) in process chemistry.

Basic Information

Product Name	(-)-Mod-Diop
CAS No.	127797-02-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(-)-Modified Diop; (2S,4S)-(-)-4-(Diphenylphosphino)-2-[(diphenylphosphino)methyl]-1,3-dioxolane; (-)-2,3-O-Isopropylidene-2,3-dihydroxy-1,4-bis(diphenylphosphino)butane; (-)-DIOP derivative; Chiral DIOP ligand; Asymmetric hydrogenation ligand; (S,S)-DIOP analog
EINECS	Contact for details

Quality Control

Our (-)-Mod-Diop is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for catalytic and synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and enantiomeric excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at room temperature (15-25°C). This compound is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain stability and catalytic activity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (ee)	≥ 99.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.