Description

2-Bromo-5-Chlorophenylacetonitrile is a versatile halogenated aromatic nitrile building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both bromine and chlorine substituents on the phenyl ring, makes it a valuable precursor for constructing complex molecules. This intermediate is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for applications such as the synthesis of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of various heterocyclic compounds and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of herbicides, fungicides, and insecticides.
• Ligand and Catalyst Development: Serves as a precursor for specialized ligands used in catalytic processes.
• Material Science Research: Employed in the synthesis of organic electronic materials and liquid crystals.
• Custom Synthesis and Contract Manufacturing: A critical building block for fine chemical producers offering bespoke synthesis services.

Basic Information

Product Name	2-Bromo-5-Chlorophenylacetonitrile
CAS No.	127792-49-8
Molecular Formula	C8H5BrClN
Molecular Weight	230.49 g/mol
Synonyms	(2-Bromo-5-chlorophenyl)acetonitrile; 2-Bromo-5-chlorobenzyl cyanide; α-Bromo-5-chlorophenylacetonitrile; 5-Chloro-2-bromophenylacetonitrile; 2-Bromo-5-chloro-α-cyanotoluene; Benzeneacetonitrile, 2-bromo-5-chloro-; (2-Bromo-5-chlorobenzyl) cyanide
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Chlorophenylacetonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.