Description

2-Chloro-n-(1,2,3,4-Tetrahydro-Naphthalen-1-Yl)-Acetamide is a specialized organic intermediate featuring a chloroacetamide moiety linked to a tetralin (tetrahydronaphthalene) backbone. This molecular architecture makes it a valuable building block for the synthesis of more complex chemical entities, particularly in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists working in the fine chemical and active pharmaceutical ingredient (API) sectors.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing complex polycyclic structures.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or plant growth regulators where the tetralin scaffold can impart specific biological activity.
• Organic Synthesis Building Block: The reactive chloroacetamide group allows for further functionalization, making it useful for constructing libraries of compounds in medicinal chemistry.
• Material Science Precursor: Potential use in the synthesis of specialty polymers or advanced organic materials that require specific aromatic-aliphatic hybrid structures.

Basic Information

Product Name	2-Chloro-n-(1,2,3,4-Tetrahydro-Naphthalen-1-Yl)-Acetamide
CAS No.	127761-16-4
Molecular Formula	C₁₂H₁₄ClNO
Molecular Weight	223.70 g/mol
Synonyms	N-(1,2,3,4-Tetrahydro-1-naphthalenyl)-2-chloroacetamide; 2-Chloro-N-(1,2,3,4-tetrahydro-1-naphthyl)acetamide; 2-Chloroacetamide, N-(1,2,3,4-tetrahydro-1-naphthalenyl)-; 1-(2-Chloroacetamido)-1,2,3,4-tetrahydronaphthalene; Tetralin-1-yl-chloroacetamide
EINECS	Contact for details

Quality Control

Our production of 2-Chloro-n-(1,2,3,4-Tetrahydro-Naphthalen-1-Yl)-Acetamide adheres to strict in-process controls and final batch testing to ensure consistency and purity suitable for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to support cGMP compliance for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.