Description

2-Pyrrolidineaceticacid,-α--Hydroxy-,Ethylester(9Ci) is a specialized organic compound belonging to the pyrrolidine class, serving as a valuable chiral building block and intermediate in advanced synthetic chemistry. Its core value lies in its structural features, which are critical for constructing complex molecules with specific stereochemistry, essential for developing active pharmaceutical ingredients (APIs) and fine chemicals. This high-purity intermediate is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries engaged in process development and scale-up.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, particularly for central nervous system (CNS) agents and other biologically active molecules.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where specific stereochemistry influences biological activity.
• Catalyst and Ligand Preparation: Serves as a precursor for developing chiral catalysts and ligands used in asymmetric synthesis to produce enantiomerically pure compounds.
• Fine Chemical Production: Employed in the manufacture of complex specialty chemicals, flavors, and fragrances requiring high-purity intermediates.
• Academic and R&D: A valuable reagent for methodological research in organic synthesis and medicinal chemistry within university and corporate laboratories.

Basic Information

Product Name	2-Pyrrolidineaceticacid,-α--Hydroxy-,Ethylester(9Ci)
CAS No.	127742-47-6
Molecular Formula	C8H15NO3
Molecular Weight	173.21 g/mol
Synonyms	Ethyl 2-(hydroxymethyl)pyrrolidine-1-acetate; α-Hydroxy-2-pyrrolidineacetic acid ethyl ester; 1-Carboxymethyl-2-hydroxymethylpyrrolidine ethyl ester; (2-Hydroxymethyl-1-pyrrolidinyl)acetic acid ethyl ester; Ethyl (2-hydroxymethylpyrrolidin-1-yl)acetate; 2-Pyrrolidineacetic acid, α-hydroxy-, ethyl ester; 1-(Ethoxycarbonylmethyl)-2-hydroxymethylpyrrolidine
EINECS	Contact for details

Quality Control

Our 2-Pyrrolidineaceticacid,-α--Hydroxy-,Ethylester(9Ci) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage, consider maintaining the material under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.