Description

(1R,4R)-Bis[(2-Methoxyphenyl)Phenylphosphino]Butane CAS NO 127686-61-7 is a chiral, bidentate phosphine ligand of high purity and defined stereochemistry. This compound matters as a critical catalyst component in asymmetric synthesis, enabling the production of enantiomerically pure intermediates for pharmaceuticals and fine chemicals. It is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-performance, stereoselective catalysts.

Application

• As a chiral ligand in asymmetric hydrogenation reactions for pharmaceutical intermediate synthesis.
• Catalyst component for enantioselective C-C and C-X bond-forming reactions in fine chemical production.
• Key reagent in the development of stereoselective processes for agrochemical active ingredients.
• Use in academic and industrial R&D for exploring new asymmetric catalytic transformations.
• Component in catalyst systems for the synthesis of specialty polymers and advanced materials.
• Employed in the preparation of chiral compounds for electronic and optoelectronic applications.

Basic Information

Product Name	(1R,4R)-Bis[(2-Methoxyphenyl)Phenylphosphino]Butane
CAS No.	127686-61-7
Molecular Formula	C36H36O2P2
Molecular Weight	562.62 g/mol
Synonyms	(R,R)-DIPAMP Derivative; (1R,4R)-Bis[(2-Methoxyphenyl)phenylphosphanyl]butane; (R,R)-Bis[(2-Methoxyphenyl)phenylphosphino]butane; (R,R)-Bis(o-Anisylphenylphosphino)butane; (R,R)-o-Anisylphenylphosphinobutane; (R,R)-DIPAMP-Butane; (R,R)-BPPB; Chiral Diphosphine Ligand 127686-61-7
EINECS	Contact for details

Quality Control

Our (1R,4R)-Bis[(2-Methoxyphenyl)Phenylphosphino]Butane is manufactured under strict quality control protocols to ensure high chemical and enantiomeric purity, which is critical for reproducible catalytic performance. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral integrity. We adhere to cGMP principles where applicable to support our clients in regulated development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. This material is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain stability and efficacy.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.