Description

Benzathine Cefotaxime is a benzathine salt derivative of the third-generation cephalosporin antibiotic, cefotaxime. This formulation is designed to enhance the stability and handling properties of the active pharmaceutical ingredient, making it a critical intermediate for the development of long-acting injectable antibiotic formulations. It is primarily utilized by pharmaceutical manufacturers and research institutions engaged in advanced antibiotic development and production.

Application

• Primary use as a key pharmaceutical intermediate in the synthesis of long-acting injectable antibiotic products.
• Research and development of novel antibacterial formulations targeting resistant bacterial strains.
• Manufacturing of veterinary medicinal products for the treatment of bacterial infections in livestock.
• Production of bulk drug substances for regulatory submission and clinical trial material.
• Used in controlled laboratory studies to investigate the pharmacokinetics of cefotaxime salts.

Basic Information

Product Name	Benzathine Cefotaxime
CAS No.	127627-69-4
Molecular Formula	C₃₂H₄₂N₈O₁₀S₂
Molecular Weight	762.85 g/mol
Synonyms	Cefotaxime Benzathine; Benzathine Salt of Cefotaxime; (6R,7R)-3-[(Acetyloxy)methyl]-7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid compound with N,N'-dibenzylethylenediamine; Cefotaxime DBED Salt; Benzathine Cefotaximate; Antibiotic Benzathine Salt
EINECS	Contact for details

Quality Control

Our Benzathine Cefotaxime is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets stringent specifications for identity, purity, and potency, aligning with pharmaceutical intermediate standards. Certificates of Analysis (COA) detailing results for assay, related substances, residual solvents, and microbiological tests are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can compromise stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Microbial Enumeration	Meets Ph. Eur. requirements

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.