Description

Vasopressin, (1-2-Mercapto)Propionic Acid-N(6)-Carboxytetramethylrhodamine-8-Lys- is a chemically modified, fluorescently labeled analog of the neurohypophysial hormone vasopressin. This compound is engineered for advanced research applications, where its fluorescent TAMRA label enables precise visualization and tracking in biological systems. It is a critical reagent for pharmaceutical R&D, neurobiology, and receptor binding studies, providing researchers with a powerful tool to investigate vasopressin receptor dynamics and cellular signaling pathways.

Application

• Fluorescent Receptor Binding Assays: Used as a high-affinity, fluorescent tracer to study vasopressin V1a and V2 receptor binding kinetics and localization.
• Cellular Imaging and Microscopy: Enables real-time visualization and tracking of vasopressin peptide internalization and receptor interactions in live or fixed cells.
• High-Throughput Screening (HTS): Serves as a key component in fluorescence-based assays for screening potential vasopressin receptor agonists or antagonists in drug discovery.
• Biochemical Research: Utilized in fluorescence polarization (FP) and fluorescence resonance energy transfer (FRET) studies to probe protein-peptide interactions.
• Neuroscience and Endocrinology Studies: Applied in research focused on understanding the role of vasopressin in social behavior, water homeostasis, and cardiovascular function.
• Diagnostic Probe Development: Acts as a prototype for developing novel diagnostic imaging agents targeting vasopressin receptors in specific tissues.

Basic Information

Product Name	Vasopressin, (1-2-Mercapto)Propionic Acid-N(6)-Carboxytetramethylrhodamine-8-Lys-
CAS No.	127303-88-2
Molecular Formula	C81H105N17O19S2
Molecular Weight	~1645.0 g/mol (Contact for exact mass)
Synonyms	[Arg8]-Vasopressin, TAMRA-labeled; TAMRA-[Cys1, Lys8]-Vasopressin; 5(6)-Carboxytetramethylrhodamine-8-Lys-Vasopressin; Fluorescein-Vasopressin Analog (TAMRA); AVP-TAMRA conjugate; TAMRA-AVP; Fluorescent Vasopressin Probe; Vasopressin, Nε-(5(6)-carboxytetramethylrhodaminyl)-L-lysine8-
EINECS	Contact for details

Quality Control

Every batch of our fluorescently labeled vasopressin is manufactured and analyzed under strict quality protocols to ensure high purity and consistent performance in sensitive research applications. Identity, purity, and labeling efficiency are verified using advanced analytical techniques including HPLC and mass spectrometry. A comprehensive Certificate of Analysis (COA), detailing purity, fluorescence properties, and analytical data, is provided with each shipment to support your research documentation and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term stability, store as supplied. Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	Red to purple solid or lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Mass spectrum consistent with molecular structure
Purity (HPLC)	≥ 95% (by area at 550 nm)
Peptide Content	≥ 80% (by weight)
Fluorescence Properties	Ex/Em ~550/575 nm (characteristic of TAMRA)
Solubility	Soluble in DMSO, DMF; slightly soluble in aqueous buffers
Water Content (K.F.)	≤ 5.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.