Description

(E)-2-(7-Methoxy-3,4-Dihydronaphthalen-1(2H)-Ylidene)Acetonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its specific stereochemistry and functional groups. This compound is a critical building block in the synthesis of complex organic molecules, offering a versatile handle for further chemical elaboration. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Organic Synthesis Building Block: Used in research-scale and process chemistry for constructing fused ring systems and introducing nitrile functionalities for further transformations.
• Chemical Research & Development: Serves as a valuable reagent in academic and industrial R&D labs for methodology development and exploring new synthetic pathways.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, dyes, and other performance materials requiring specific molecular architectures.

Basic Information

Product Name	(E)-2-(7-Methoxy-3,4-Dihydronaphthalen-1(2H)-Ylidene)Acetonitrile
CAS No.	127299-26-7
Molecular Formula	C₁₄H₁₃NO
Molecular Weight	211.26 g/mol
Synonyms	2-[(E)-(7-Methoxy-3,4-dihydro-1(2H)-naphthalenylidene)]acetonitrile; (E)-2-(7-Methoxy-1,2,3,4-tetrahydronaphthalen-1-ylidene)acetonitrile; 7-Methoxy-1-(cyanomethylene)-1,2,3,4-tetrahydronaphthalene; 1,2,3,4-Tetrahydro-7-methoxy-1-naphthalenylideneacetonitrile; Tetralone cyanomethylene derivative
EINECS	Contact for details

Quality Control

Our production of (E)-2-(7-Methoxy-3,4-Dihydronaphthalen-1(2H)-Ylidene)Acetonitrile adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the exacting standards required for pharmaceutical R&D and production. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.