Description

Vasopressin, (1-(2-Mercapto)Propionic Acid)-N(6)-5-Dimethylaminonaphthalene-1-Sulfonyl-8-Lys- is a chemically modified derivative of the neurohypophysial hormone vasopressin, designed for advanced biochemical research and diagnostic applications. This compound is particularly valuable for its fluorescent labeling via the dansyl (5-dimethylaminonaphthalene-1-sulfonyl) group, enabling sensitive detection and tracking in complex biological systems. It is primarily utilized by researchers in pharmaceutical development, neuroendocrinology, and clinical diagnostics who require high-purity, well-characterized peptide analogs for receptor binding studies, assay development, and tracer synthesis.

Application

• Biochemical Research: Used as a fluorescently labeled tracer in competitive binding assays and receptor studies for vasopressin and oxytocin receptors.
• Diagnostic Kit Development: Serves as a critical component in the development of sensitive immunoassays and fluorescence-based diagnostic tests.
• Pharmaceutical R&D: Employed in drug discovery programs targeting vasopressin pathways, useful for high-throughput screening and mechanism-of-action studies.
• Neuroscience Studies: Facilitates the visualization and quantification of vasopressin receptor distribution and dynamics in neural tissues.
• Peptide Chemistry Reference Standard: Acts as a high-purity reference material for analytical method development and validation in QC laboratories.
• Metabolic Pathway Analysis: Used to study the metabolism and clearance of vasopressin analogs in preclinical models.

Basic Information

Product Name	Vasopressin, (1-(2-Mercapto)Propionic Acid)-N(6)-5-Dimethylaminonaphthalene-1-Sulfonyl-8-Lys-
CAS No.	127290-94-2
Molecular Formula	C64H91N15O16S3
Molecular Weight	1430.7 g/mol
Synonyms	[1-(2-Mercaptopropionic acid), 8-Lysine(N6-dansyl)]vasopressin; Dansyl-Lys8-vasopressin; [1-β-Mercapto-β,β-cyclopentamethylenepropionic acid), 8-Lysine(N6-5-dimethylaminonaphthalene-1-sulfonyl)]vasopressin; Fluorescently-labeled vasopressin; Vasopressin dansyl derivative; [Lys8(Nε-dansyl)]-Vasopressin; ADH fluorescent analog; Arginine vasopressin dansyl conjugate
EINECS	Contact for details

Quality Control

Our Vasopressin, (1-(2-Mercapto)Propionic Acid)-N(6)-5-Dimethylaminonaphthalene-1-Sulfonyl-8-Lys- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and amino acid analysis to ensure structural integrity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications and test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Consistent with molecular weight
Purity (HPLC)	≥ 95.0%
Single Largest Impurity (HPLC)	≤ 2.0%
Total Impurities (HPLC)	≤ 5.0%
Water Content (KF)	≤ 5.0%
Peptide Content (Amino Acid Analysis)	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.