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Inhibin A-Subunit Fragment 1-32 Human CAS NO 127119-75-9
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CAS No.:127119-75-9
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Inhibin A-Subunit Fragment 1-32 Human is a synthetic peptide fragment corresponding to the N-terminal region of the inhibin alpha subunit. This compound is a critical research tool for studying the structure, function, and signaling pathways of inhibin, a key regulatory hormone in the reproductive system. It is primarily utilized by researchers and developers in the fields of endocrinology, reproductive biology, and biopharmaceutical development for applications such as immunoassay development, antibody production, and receptor binding studies.
Application
- Immunoassay Development & Calibration: Serves as a precise reference standard and calibrator in ELISA and RIA kits for quantifying inhibin A levels in biological samples.
- Antibody Production & Characterization: Used as an immunogen to generate specific polyclonal or monoclonal antibodies targeting the inhibin alpha subunit.
- Biochemical & Receptor Binding Studies: Essential for investigating the interaction between inhibin and its receptors (e.g., betaglycan, ActRII) to elucidate downstream signaling mechanisms.
- Endocrine & Reproductive Research: A fundamental reagent for studying the role of inhibin in folliculogenesis, spermatogenesis, and feedback regulation of FSH secretion.
- Quality Control in Biomanufacturing: Employed as a system suitability standard in the quality control of therapeutic proteins and related biopharmaceutical products.
- Cell Culture & In Vitro Studies: Applied in cell-based assays to examine the biological effects of inhibin fragments on target tissues.
Basic Information
| Product Name | Inhibin A-Subunit Fragment 1-32 Human |
| CAS No. | 127119-75-9 |
| Molecular Formula | C152H251N45O47S2 |
| Molecular Weight | 3484.1 g/mol |
| Synonyms | Inhibin alpha (1-32); INHA (1-32); Inhibin A Subunit (1-32); Human Inhibin Alpha Chain Fragment 1-32; Inhibin-alpha 1-32; INH-alpha(1-32); Inhibin A α-subunit fragment 1-32 |
| EINECS | Contact for details |
Quality Control
Our Inhibin A-Subunit Fragment 1-32 Human is manufactured under stringent conditions to ensure the highest standards of purity and batch-to-batch consistency. Each lot undergoes comprehensive analytical characterization, including reversed-phase HPLC, mass spectrometry (MS), and amino acid analysis. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and peptide content.
Storage
Preserve in a tightly closed container, protected from light. Store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white lyophilized powder |
| Identification (HPLC) | Retention time corresponds to reference standard |
| Identification (MS) | Molecular weight confirmed by mass spectrometry |
| Purity (HPLC) | ≥ 95% |
| Peptide Content | ≥ 80% (by weight) |
| Water Content (KF) | ≤ 5.0% |
| Acetate Content (HPIC) | ≤ 10.0% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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