Description

Glutamic Acid, n-Acetyl-2-Methyl- is a chemically modified derivative of glutamic acid, featuring acetylation and methylation at specific positions. This structural modification makes it a valuable chiral building block and intermediate for advanced organic synthesis. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and fine chemical industries for developing novel compounds, including potential active pharmaceutical ingredients (APIs) and specialty biochemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new drug candidates and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a specialized substrate or precursor in enzymatic studies and metabolic pathway investigations.
• Peptide Synthesis: Acts as a protected or modified amino acid derivative for the synthesis of complex peptides and peptidomimetics.
• Fine Chemical Production: Employed as a high-value intermediate in the manufacture of specialty chemicals, agrochemicals, and advanced materials.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or starting material in stereoselective synthesis to create enantiomerically pure compounds.

Basic Information

Product Name	Glutamic Acid, n-Acetyl-2-Methyl-
CAS No.	127027-18-3
Molecular Formula	C8H13NO5
Molecular Weight	203.19 g/mol
Synonyms	N-Acetyl-2-methylglutamic acid; 2-Methyl-N-acetylglutamic acid; (2S)-2-Acetamidopentanedioic acid (related stereoisomer); Acetyl-2-methylglutamate; Modified Glutamate Derivative; 2-Methylglutamic acid N-acetate; N-Acetyl-α-methylglutamic acid
EINECS	Contact for details

Quality Control

Our Glutamic Acid, n-Acetyl-2-Methyl- is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for assay, chiral purity, and impurity profiles are available upon request. We can support development projects with material meeting custom purity specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent absorption of moisture from the air.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	Contact for details
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.