Description

Gadobenate Dimeglumine is a paramagnetic contrast agent used in diagnostic magnetic resonance imaging (MRI). Its primary value lies in its dual hepatobiliary and renal excretion pathway, which provides enhanced imaging of the liver and central nervous system vasculature. This compound is essential for pharmaceutical manufacturers, research institutions, and diagnostic centers developing and producing advanced MRI contrast media. The product is supplied under stringent quality control to ensure batch-to-batch consistency and reliability for critical medical applications.

Application

• MRI Contrast Media: Primary active pharmaceutical ingredient (API) in formulations for magnetic resonance imaging.
• Hepatobiliary Imaging: Used for contrast-enhanced MRI of the liver to detect and characterize focal lesions.
• Central Nervous System (CNS) Imaging: Employed in contrast-enhanced MR angiography (MRA) for visualization of the CNS vasculature.
• Pharmaceutical Research & Development: Serves as a key reference standard and intermediate in the development of new diagnostic agents.
• Clinical Diagnostics: Integral component in finished drug products used in hospital and clinical radiology settings.

Basic Information

Product Name	Gadobenate Dimeglumine
CAS No.	127000-20-8
Molecular Formula	C22H28GdN3O11 • 2C7H17NO5
Molecular Weight	1058.98 g/mol (for the dimeglumine salt)
Synonyms	Gadobenic acid dimeglumine salt; Gd-BOPTA; Gadobenate Dimeglumine; MultiHance (brand name); Gadobenic Acid Dimeglumine; B-19036; (4-Carboxy-5,8,11-tris(carboxymethyl)-1-phenyl-2-oxa-5,8,11-triazatridecan-13-oato(5-))gadolinium Hydrogen Compound with 1-Deoxy-1-(methylamino)-D-glucitol (2:1); Gadolinium chelate of benzyloxypropionic tetraacetate
EINECS	Contact for details

Quality Control

Our Gadobenate Dimeglumine is manufactured and tested to meet the exacting standards required for pharmaceutical active ingredients. Quality assurance protocols are designed to ensure compliance with ICH guidelines and relevant pharmacopoeial monographs. A comprehensive Certificate of Analysis (COA) is provided with each batch, detailing purity, identity, and impurity profiles. We support audits and can provide documentation for regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent absorption of atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Free Gadolinium	≤ 0.01%
Free Dimeglumine	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.1%; Total impurities ≤ 0.5%
Bacterial Endotoxins	< 0.5 EU/mg
Sterility (if applicable)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.