Description

Cionin CAS NO 126985-56-6 is a synthetic peptide with specific biological activity, primarily recognized for its role as a cholecystokinin (CCK) receptor agonist. This compound is a critical research tool for studying gastrointestinal physiology, satiety signaling, and central nervous system functions. It is essential for pharmaceutical R&D, academic research, and the development of diagnostic assays targeting the CCK pathway.

Application

• Pharmacological Research: Used as a reference standard and active agent in studies investigating cholecystokinin receptor subtypes (CCKA and CCKB) and their signaling pathways.
• Gastrointestinal Studies: Employed in vitro and in vivo to stimulate pancreatic enzyme secretion, gallbladder contraction, and gut motility for physiological and disease model research.
• Neuroscience Research: Applied in studies exploring the role of CCK in anxiety, satiety, nociception, and dopamine modulation within the central nervous system.
• Biomarker & Assay Development: Serves as a critical component in the development and validation of immunoassays (ELISA, RIA) and receptor binding assays for CCK-related biomarkers.
• Drug Discovery Screening: Utilized as a control agonist in high-throughput screening (HTS) campaigns to identify novel CCK receptor modulators, antagonists, or allosteric regulators.

Basic Information

Product Name	Cionin
CAS No.	126985-56-6
Molecular Formula	C56H73N13O11S
Molecular Weight	1120.33 g/mol
Synonyms	Cionin Peptide; H-Asp-Tyr(SO3H)-Met-Gly-Trp-Met-Asp-Phe-NH2; Sulfated Cholecystokinin Octapeptide (CCK-8S); Cholecystokinin Sulfated Octapeptide; CCK-8 Sulfate; Asp-Tyr(SO3H)-Met-Gly-Trp-Met-Asp-Phe-amide; Sincalide analog; CCK Octapeptide, Sulfated
EINECS	Contact for details

Quality Control

Our Cionin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). We provide full traceability and Certificates of Analysis (COA) detailing purity, peptide content, and residual solvent levels, ensuring compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, consider under an inert atmosphere. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by AAA)
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Composition	Within ±10% of theoretical
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.