Description

3-(2,3-Dihydroxypropyl)Deoxyuridine is a modified nucleoside derivative, a key building block in advanced pharmaceutical and biochemical research. This compound matters for its role as a versatile intermediate in the synthesis of novel antiviral agents and nucleotide analogs, enabling the development of targeted therapies. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on antiviral drug discovery and diagnostic probe development.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel antiviral and anticancer nucleotide analogs.
• Biochemical Research: Used as a modified substrate in enzymatic studies and for investigating DNA/RNA metabolism and repair mechanisms.
• Pro-drug Development: Serves as a key building block for creating targeted pro-drugs with enhanced cellular uptake and specificity.
• Diagnostic Agent Synthesis: Employed in the development of labeled nucleotides for diagnostic assays and molecular imaging probes.
• Antiviral Agent Research: Integral to R&D programs aimed at discovering new treatments for viral infections by mimicking natural nucleosides.
• Academic & Institutional Research: A valuable tool for universities and research institutes studying nucleoside chemistry and its biological applications.

Basic Information

Product Name	3-(2,3-Dihydroxypropyl)Deoxyuridine
CAS No.	126863-75-0
Molecular Formula	C12H18N2O7
Molecular Weight	302.28 g/mol
Synonyms	3-(2,3-Dihydroxypropyl)-2'-deoxyuridine; 1-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3-(2,3-dihydroxypropyl)pyrimidine-2,4-dione; 3-(2,3-Dihydroxypropyl)dUrd; 3-HP-dU; Modified Deoxyuridine; DHP-Deoxyuridine; Nucleoside Derivative; Antiviral Nucleoside Intermediate
EINECS	Contact for details

Quality Control

Our 3-(2,3-Dihydroxypropyl)Deoxyuridine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.