Description

Bapta, Tetrasodium Salt is a high-purity, water-soluble chelating agent and calcium buffer widely used in biochemical and diagnostic applications. Its primary value lies in its high affinity and selectivity for calcium ions (Ca²⁺) over magnesium ions (Mg²⁺), making it an essential tool for controlling and studying calcium-dependent biological processes. This compound is critical for researchers and manufacturers in the life sciences, pharmaceutical development, and in-vitro diagnostic (IVD) reagent production who require precise metal ion buffering.

Application

• Calcium Ion Buffering in Biochemical Research: Used to create stable, defined concentrations of free Ca²⁺ in cell culture media, enzyme assays, and receptor-ligand binding studies.
• In-Vitro Diagnostic (IVD) Reagents: A key component in clinical chemistry analyzers and test kits, particularly for assays measuring enzymes or biomarkers sensitive to calcium concentration.
• Pharmaceutical Formulation: Employed as a stabilizing agent in certain biopharmaceuticals and injectable solutions where control of divalent cations is necessary.
• Molecular Biology: Utilized in DNA/RNA extraction and purification protocols to inhibit calcium-dependent nucleases.
• Cell Biology & Physiology Studies: Essential for experiments investigating calcium signaling, muscle contraction, neurotransmitter release, and apoptosis.
• Industrial Process Chelation: Acts as a sequestrant in specific high-purity industrial processes where control of calcium scaling is required.

Basic Information

Product Name	Bapta, Tetrasodium Salt
CAS No.	126824-24-6
Molecular Formula	C22H28N2O11Na4
Molecular Weight	604.4 g/mol (anhydrous basis)
Synonyms	BAPTA, Tetrasodium Salt; 1,2-Bis(o-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid tetrasodium salt; BAPTA-4Na; BAPTA Tetrasodium; Tetrasodium 1,2-bis(2-aminophenoxy)ethane-N,N,N′,N′-tetraacetate; EGTA, Tetrasodium Salt (related compound); AAT, Tetrasodium Salt; Calcium Chelator BAPTA-4Na
EINECS	Contact for details

Quality Control

Our Bapta, Tetrasodium Salt is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity, identity, and consistency suitable for sensitive research and diagnostic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, heavy metals, and other critical parameters is provided with every shipment to guarantee traceability and compliance with your quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed in a desiccated environment to prevent absorption of moisture and CO₂ from the air, which can affect performance.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
pH (1% Solution)	7.0 - 9.0
Water Content (KF)	≤ 5.0%
Heavy Metals (as Pb)	≤ 20 ppm
Calcium Binding Capacity	Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.