Description

2-Thiazoleacetonitrile, 4-Hydroxy- is a specialized heterocyclic nitrile building block of significant interest in advanced organic synthesis. Its unique structure, featuring both a thiazole ring and a reactive nitrile group, makes it a valuable precursor for constructing complex molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly for molecules containing thiazole pharmacophores.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic framework.
• Ligand and Catalyst Development: Acts as a precursor for synthesizing specialized ligands used in metal-catalyzed reactions and coordination chemistry.
• Material Science Research: Employed in the development of advanced organic materials, such as conductive polymers or liquid crystals, due to its electron-rich thiazole component.
• Chemical Biology Probes: Utilized to build molecular probes for studying biological processes and enzyme mechanisms.

Basic Information

Product Name	2-Thiazoleacetonitrile, 4-Hydroxy-
CAS No.	126743-35-9
Molecular Formula	C5H4N2OS
Molecular Weight	140.16 g/mol
Synonyms	4-Hydroxy-2-thiazoleacetonitrile; 4-Hydroxythiazole-2-acetonitrile; (4-Hydroxy-1,3-thiazol-2-yl)acetonitrile; 2-(Cyanomethyl)-4-hydroxythiazole; 4-Hydroxy-2-thiazolylacetonitrile
EINECS	Contact for details

Quality Control

Our 2-Thiazoleacetonitrile, 4-Hydroxy- is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support our clients with full traceability and documentation to meet the stringent requirements of pharmaceutical and agrochemical development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.