Description

Ethynyl-Benzene, also known as phenylacetylene, is a versatile terminal alkyne building block of significant importance in synthetic organic chemistry. Its high reactivity, particularly in metal-catalyzed cross-coupling and cycloaddition reactions, makes it indispensable for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where it serves as a key precursor for active ingredients, specialty polymers, and liquid crystal intermediates.

Application

• Pharmaceutical Intermediates: A critical building block for the synthesis of various drug candidates and active pharmaceutical ingredients (APIs), particularly those requiring alkyne functional groups for further derivatization.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators that incorporate phenylacetylene motifs for enhanced biological activity.
• Material Science & Polymer Chemistry: Serves as a monomer or co-monomer in the synthesis of specialty polymers, conductive materials, and liquid crystals for electronic and optical applications.
• Organic Synthesis & Catalysis: A fundamental reagent in Sonogashira, Glaser, and other metal-catalyzed cross-coupling reactions to form carbon-carbon bonds, widely used in academic and industrial R&D.
• Fine Chemical Production: Employed in the manufacture of flavors, fragrances, dyes, and other high-value specialty chemicals.

Basic Information

Product Name	Ethynyl-Benzene
CAS No.	126716-66-3
Molecular Formula	C8H6
Molecular Weight	102.13 g/mol
Synonyms	Phenylacetylene; Benzene, ethynyl-; 1-Ethynylbenzene; Acetylene, phenyl-; Ethynylbenzene; Phenylethyne; (Phenylethynyl)benzene (for dimer); Contact for details on additional trade names.
EINECS	Contact for details

Quality Control

Our Ethynyl-Benzene is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to verify identity, potency, and impurity profiles. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids, oxidizers, and bases. Recommended storage temperature is 2-8°C for long-term stability. Keep container tightly sealed when not in use to prevent moisture absorption and evaporation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Individual impurity ≤ 1.0%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.