Description

n-(4-Trifluoromethylphenyl)Glycine Methyl Ester is a high-value fluorinated amino acid derivative, serving as a critical synthetic intermediate. Its core value lies in introducing the trifluoromethylphenyl moiety, a key pharmacophore known to enhance metabolic stability and lipophilicity in bioactive molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the trifluoromethyl group improves efficacy and environmental profile.
• Peptidomimetics & Drug Discovery: Employed in medicinal chemistry for creating peptide analogs and small molecule libraries to explore new drug candidates.
• Liquid Crystal & Material Science: Acts as a precursor for fluorinated organic materials used in electronic displays and advanced polymers.
• Chemical Research & Development: Serves as a versatile reagent in academic and industrial R&D for introducing fluorinated aromatic glycine structures.

Basic Information

Product Name	n-(4-Trifluoromethylphenyl)Glycine Methyl Ester
CAS No.	126689-82-5
Molecular Formula	C10H10F3NO2
Molecular Weight	233.19 g/mol
Synonyms	Methyl 2-amino-2-[4-(trifluoromethyl)phenyl]acetate; 2-Amino-2-[4-(trifluoromethyl)phenyl]acetic acid methyl ester; (4-Trifluoromethylphenyl)glycine methyl ester; Methyl (4-trifluoromethylphenyl)glycinate; Glycine, N-[4-(trifluoromethyl)phenyl]-, methyl ester; Methyl α-amino-4-(trifluoromethyl)benzeneacetate
EINECS	Contact for details

Quality Control

Our n-(4-Trifluoromethylphenyl)Glycine Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.