Description

S,S'-Bis(tert-Butyloxycarbonyl-Cysteinylalanine Methyl Ester) is a high-purity, protected dipeptide building block essential for advanced peptide synthesis. This compound is critical for researchers and manufacturers requiring precise control over molecular structure and stereochemistry in complex peptide sequences. It is primarily utilized in pharmaceutical R&D for the development of novel therapeutic peptides and in academic laboratories for biochemical studies.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled assembly of cysteine-containing peptide chains.
• Pharmaceutical Research & Development: Used in the synthesis of peptide-based drug candidates, including enzyme inhibitors and receptor agonists/antagonists.
• Bioconjugation Chemistry: Serves as a precursor for creating peptide-protein or peptide-small molecule conjugates due to its protected thiol groups.
• Combinatorial Chemistry Libraries: A valuable building block for generating diverse peptide libraries for high-throughput screening.
• Academic & Biochemical Research: Employed in studies of protein folding, disulfide bond formation, and structure-activity relationships (SAR).
• Custom Peptide Service Providers: A critical raw material for companies offering bespoke peptide synthesis services to the biotech and pharmaceutical industries.

Basic Information

Product Name	S,S'-Bis(tert-Butyloxycarbonyl-Cysteinylalanine Methyl Ester)
CAS No.	126686-69-9
Molecular Formula	C23H40N2O8S2
Molecular Weight	552.70 g/mol
Synonyms	Boc-Cys(Boc)-Ala-OMe; (2R)-2-[[(2R)-2-[(2-Methylpropan-2-yl)oxycarbonylamino]-3-[(2-methylpropan-2-yl)oxycarbonylsulfanyl]propanoyl]amino]propanoic acid methyl ester; Nα,S-Bis-Boc-Cysteinylalanine Methyl Ester; Boc-Cys(Boc)-Ala-Me; Methyl N-[(2R)-2-[[(2R)-3-[(tert-butoxy)carbonyl]sulfanyl-2-[(tert-butoxy)carbonylamino]propanoyl]amino]propanoyl]alaninate; Dipeptide Boc-Cys(Boc)-Ala-OMe
EINECS	Contact for details

Quality Control

Our S,S'-Bis(tert-Butyloxycarbonyl-Cysteinylalanine Methyl Ester) is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines for pharmaceutical intermediates, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation or storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.