Description

Benzonitrile, 2-Amino-3,5-Difluoro- is a high-purity fluorinated aromatic nitrile building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both an amino group and fluorine substituents on the benzonitrile core, makes it a versatile precursor for creating complex heterocycles and functional materials. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients. Its reliable quality and consistent supply are critical for accelerating innovation in drug discovery and specialty chemical development.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where the fluorine atoms enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of fluorinated polymers, liquid crystals, and organic electronic materials for their unique electronic and surface properties.
• Dye and Pigment Intermediate: Utilized in the manufacture of specialized fluorinated dyes and pigments for high-performance applications.

Basic Information

Product Name	Benzonitrile, 2-Amino-3,5-Difluoro-
CAS No.	126674-94-0
Molecular Formula	C7H4F2N2
Molecular Weight	154.12 g/mol
Synonyms	2-Amino-3,5-difluorobenzonitrile; 3,5-Difluoro-2-aminobenzonitrile; 2-Amino-3,5-difluorophenyl cyanide; 2-Cyano-4,6-difluoroaniline; 4,6-Difluoro-2-cyanobenzenamine; 2-Amino-3,5-difluorobenzene carbonitrile; Benzonitrile, 2-amino-3,5-difluoro- (9CI)
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-3,5-Difluorobenzonitrile is manufactured and tested under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, and NMR to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment. Our quality commitment ensures the material meets the stringent requirements for research and cGMP-grade pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.