Description

3-Hydroxy Desoxy-Dihydroartemisinin is a key synthetic intermediate and derivative of the potent antimalarial compound artemisinin. This high-purity intermediate is critical for pharmaceutical research and development, particularly in the synthesis of novel artemisinin-based drug candidates and reference standards. It is primarily utilized by research institutions, pharmaceutical manufacturers, and fine chemical suppliers engaged in the development of next-generation antimalarial and anticancer therapeutics.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel artemisinin derivatives and analogs with potential therapeutic activity.
• Antimalarial Drug Research: Used in R&D to study structure-activity relationships and develop new compounds to combat drug-resistant malaria strains.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.
• Anticancer Research: Investigated as a precursor for developing artemisinin-derived compounds with potential anticancer properties.
• Chemical Synthesis: Employed in organic synthesis for the preparation of complex molecules due to its unique sesquiterpene lactone structure.
• Academic & Institutional Research: Used in universities and research institutes for pharmacological studies and biochemical pathway analysis.

Basic Information

Product Name	3-Hydroxy Desoxy-Dihydroartemisinin
CAS No.	126641-61-0
Molecular Formula	C15H24O4
Molecular Weight	268.35 g/mol
Synonyms	3-Hydroxydeoxy-Dihydroartemisinin; 3α-Hydroxy-11-epi-artemisinin; 10-Desoxy-3α-hydroxy-Dihydroartemisinin; 3-Hydroxy-10-desoxydihydroartemisinin; 3-Hydroxy-10-deoxydihydroartemisinin; Arteannuin B derivative; (3R,5aS,6R,8aS,9R,10S,12R,12aR)-Decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-ol
EINECS	Contact for details

Quality Control

Our 3-Hydroxy Desoxy-Dihydroartemisinin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis to ensure it meets the stringent requirements for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.