Description

2-Cefetamet Pivoxil is a prodrug ester of the third-generation cephalosporin antibiotic, cefetamet. This compound is specifically designed to enhance oral bioavailability, making it a critical intermediate in the synthesis of effective oral antibacterial medications. It is primarily utilized by pharmaceutical manufacturers and research institutions engaged in the development and production of advanced antibiotic formulations. The product is supplied as a high-purity intermediate to ensure the efficacy and safety of the final drug product.

Application

• Pharmaceutical Intermediate: Primary use as a key precursor in the synthesis of the active pharmaceutical ingredient (API) cefetamet.
• Oral Antibiotic Production: Essential for manufacturing oral dosage forms of cephalosporin antibiotics, improving patient compliance over injectable forms.
• Research & Development: Used in pharmaceutical R&D for studying prodrug metabolism, pharmacokinetics, and developing new antibiotic derivatives.
• Antibacterial Formulations: Incorporated into the production of broad-spectrum antibacterial drugs targeting respiratory, urinary, and soft tissue infections.
• GMP Manufacturing: Sourced by contract manufacturing organizations (CMOs) and API producers operating under Good Manufacturing Practice (GMP) standards.
• Reference Standard: Serves as a chemical reference standard in quality control laboratories for analytical method development and validation.

Basic Information

Product Name	2-Cefetamet Pivoxil
CAS No.	126617-54-7
Molecular Formula	C₂₀H₂₅N₅O₇S₂
Molecular Weight	511.57 g/mol
Synonyms	Cefetamet Pivoxil; (6R,7R)-7-[(Z)-2-(2-Amino-4-thiazolyl)-2-methoxyiminoacetamido]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid Pivaloyloxymethyl Ester; Ro 15-8075; Cefetamet Pivoxil Ester; Cefetamet Pivaloyloxymethyl Ester; Cefetamet Pivoxil Intermediate; Pivoxil Ester of Cefetamet
EINECS	Contact for details

Quality Control

Our 2-Cefetamet Pivoxil is manufactured under strict quality systems to meet the exacting requirements of pharmaceutical applications. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identification by IR and NMR, and control of specified impurities. We provide full traceability and Certificates of Analysis (COA) are supplied with every shipment, ensuring compliance with relevant internal specifications and supporting our customers' regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0%
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.