Description

Boc-3-(1-Pyrenyl)-D-Alanine is a specialized, protected amino acid derivative featuring a bulky, fluorescent pyrenyl side chain. This compound is a critical building block in advanced peptide synthesis and medicinal chemistry research, offering precise stereochemical control and unique photophysical properties. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers developing novel peptide-based therapeutics, fluorescent probes, and advanced materials.

Application

• Peptide Synthesis: Serves as a key chiral intermediate for incorporating the D-enantiomer of a pyrene-labeled amino acid into custom peptide sequences, enabling structure-activity relationship (SAR) studies.
• Fluorescent Probe Development: Used to synthesize peptides and proteins tagged with a pyrene fluorophore for biophysical studies, including protein-protein interactions, folding kinetics, and localization assays.
• Medicinal Chemistry Research: Acts as a building block for creating peptide mimetics and constrained analogs in drug discovery programs targeting various disease pathways.
• Material Science: Employed in the synthesis of functionalized polymers and supramolecular assemblies where the pyrene moiety provides self-assembly or sensing capabilities.
• Academic & Institutional Research: Essential for fundamental studies in organic synthesis, photochemistry, and asymmetric catalysis due to its unique structural features.

Basic Information

Product Name	Boc-3-(1-Pyrenyl)-D-Alanine
CAS No.	126613-96-5
Molecular Formula	C24H23NO4
Molecular Weight	389.45 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-3-(1-pyrenyl)-D-alanine; (R)-2-((tert-Butoxycarbonyl)amino)-3-(pyren-1-yl)propanoic acid; Boc-D-3-(1-Pyrenyl)alanine; Boc-D-1-Pyrenylalanine; tert-Butyloxycarbonyl-D-3-(1-pyrenyl)alanine; N-Boc-3-(1-pyrenyl)-D-alanine; D-Boc-1-pyrenylalanine
EINECS	Contact for details

Quality Control

Every batch of Boc-3-(1-Pyrenyl)-D-Alanine is produced and tested under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and enantiomeric excess meet the exacting standards required for research and development. A detailed Certificate of Analysis (COA) with HPLC purity, chiral purity, and spectroscopic data is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee (D-isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.