Description

(R)-1-Cyano-2,2-Dimethyl-1-Propyl Acetate is a high-value chiral intermediate characterized by its cyano and ester functional groups. This compound matters for its role as a critical building block in the synthesis of complex, optically active molecules, particularly in the pharmaceutical sector. It is primarily needed by research and development teams and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries for creating active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), especially in neurological and cardiovascular drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced, stereospecific pesticides and herbicides.
• Catalyst and Ligand Preparation: Serves as a precursor for developing novel chiral catalysts and ligands used in asymmetric synthesis.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.
• Academic and Industrial R&D: A valuable reagent for method development and exploring new synthetic pathways in organic chemistry laboratories.

Basic Information

Product Name	(R)-1-Cyano-2,2-Dimethyl-1-Propyl Acetate
CAS No.	126567-38-2
Molecular Formula	C8H13NO2
Molecular Weight	155.19 g/mol
Synonyms	(R)-1-Cyano-2,2-dimethylpropyl acetate; (R)-2,2-Dimethyl-3-cyanopropyl acetate; (R)-3-Cyano-2,2-dimethylpropyl acetate; (R)-1-Acetoxy-3-cyano-2,2-dimethylpropane; (R)-Neopentylglycol cyanohydrin acetate; (R)-NC-CH2-C(CH3)2-CH2-O-CO-CH3; (R)-1-Cyano-2,2-dimethylpropyl ethanoate
EINECS	Contact for details

Quality Control

Our (R)-1-Cyano-2,2-Dimethyl-1-Propyl Acetate is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) and standard purity assays, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) with detailed specifications are provided for each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.