Description

o-(Fluoromethyl)Hydroxylamine Hydrochloride is a specialized organic salt of significant interest in advanced synthetic chemistry. This compound serves as a versatile building block for introducing fluorinated hydroxylamine motifs into target molecules, a key step in the development of novel pharmaceuticals and agrochemicals. It is primarily utilized by research scientists and process chemists in the pharmaceutical, agrochemical, and material science industries for the synthesis of complex, high-value intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of fluorinated drug candidates, including potential enzyme inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, pesticides, and plant growth regulators with enhanced properties.
• Chemical Biology & Proteomics: Acts as a reagent for the selective modification of proteins and peptides, useful in activity-based protein profiling (ABPP) and bioconjugation.
• Material Science Precursor: Employed in the synthesis of fluorinated polymers and specialty materials with tailored surface characteristics.
• Organic Synthesis Building Block: Facilitates the introduction of N-O and C-F functional groups in complex molecule construction for research and scale-up.

Basic Information

Product Name	o-(Fluoromethyl)Hydroxylamine Hydrochloride
CAS No.	126483-47-4
Molecular Formula	C₂H₅ClFNO
Molecular Weight	113.52 g/mol
Synonyms	N-(Fluoromethoxy)amine hydrochloride; (Fluoromethoxy)amine HCl; O-(Fluoromethyl)hydroxylamine HCl; Hydroxylamine, O-(fluoromethyl)-, hydrochloride; 2-Fluoro-N-hydroxy-methanaminium chloride; N-Hydroxy-2-fluoro-methanaminium chloride; Aminooxyfluoromethane hydrochloride
EINECS	Contact for details

Quality Control

Our o-(Fluoromethyl)Hydroxylamine Hydrochloride is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and titration, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.