Description

Fibromodulin is a small leucine-rich proteoglycan (SLRP) that plays a crucial role in regulating collagen fibrillogenesis and tissue organization. Its primary commercial value lies in its application as a high-purity biochemical reagent for advanced research and development in the life sciences. This product is essential for researchers and developers in the fields of connective tissue biology, osteoarthritis research, wound healing studies, and regenerative medicine.

Application

• Biomedical Research: Used as a key reagent in studies investigating extracellular matrix (ECM) assembly, collagen fiber formation, and tissue morphogenesis.
• Osteoarthritis & Cartilage Research: Employed in in vitro and in vivo models to understand its role in cartilage homeostasis and as a potential biomarker or therapeutic target.
• Wound Healing & Tissue Engineering: Applied in research focused on modulating scar formation and developing advanced biomaterials for skin regeneration and repair.
• Cell Signaling Studies: Utilized to investigate interactions with growth factors (e.g., TGF-β) and other ECM components in cellular communication pathways.
• Diagnostic Development: Serves as a reference standard or antigen in the development of immunoassays for detecting ECM-related pathologies.
• Biopharmaceutical Production: May be used in process development and quality control for biologics targeting musculoskeletal diseases.

Basic Information

Product Name	Fibromodulin
CAS No.	126468-95-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	FMOD; SLRP; Proteoglycan, Fibromodulin; ECM2; Fibromodulin Precursor; Leucine-Rich Proteoglycan; Cartilage Matrix Protein
EINECS	Contact for details

Quality Control

Our Fibromodulin is produced under stringent conditions to ensure batch-to-batch consistency and high biological activity. Each lot undergoes rigorous quality testing, including purity analysis and functional characterization. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and biological activity is provided with every shipment to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. Avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive) and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (SDS-PAGE)	Complies
Purity (HPLC)	≥ 95%
Protein Content	≥ 90%
Endotoxin Level	< 1.0 EU/μg
Biological Activity	Determined by functional assay (e.g., collagen binding)
Solubility	Soluble in appropriate aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.