Description

Bis-Propargyl-Peg4 is a specialized bifunctional polyethylene glycol (PEG) derivative featuring terminal propargyl groups. This compound is a critical building block in click chemistry, enabling highly efficient and selective conjugation reactions, particularly copper-catalyzed azide-alkyne cycloaddition (CuAAC). It is essential for researchers and manufacturers in the pharmaceutical and biotech sectors who require reliable, high-purity linkers for creating complex molecular architectures, such as antibody-drug conjugates (ADCs), peptide modifications, and advanced polymer materials.

Application

• Key reagent in click chemistry for bioconjugation and polymer synthesis.
• Bifunctional linker for the synthesis of antibody-drug conjugates (ADCs) and other targeted therapeutics.
• Building block for creating PEGylated prodrugs and functionalized biomaterials.
• Intermediate in the development of hydrogels and cross-linked polymer networks for drug delivery.
• Tool compound for surface functionalization and material science applications.
• Used in diagnostic assay development for attaching detection labels.

Basic Information

Item	Details
Product Name	Bis-Propargyl-Peg4
CAS No.	126422-58-0
Molecular Formula	C18H30O6
Molecular Weight	342.43 g/mol
Synonyms	1,11-Bis(prop-2-yn-1-yloxy)-3,6,9-trioxaundecane; Propargyl-PEG4-propargyl; α,ω-Bis-propargyl tetraethylene glycol; Bis(propargyl) PEG4; 3,6,9,12-Tetraoxatetradeca-1,14-diyne; PEG4-dipropargyl ether; Tetraethylene glycol dipropargyl ether
EINECS	Contact for details

Quality Control

Our Bis-Propargyl-Peg4 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent performance for sensitive research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. The product is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.