Description

Norleucine, n-[(Phenylmethoxy)Carbonyl]-, Phenylmethyl Ester is a protected amino acid derivative, specifically a Cbz-protected norleucine benzyl ester, with the CAS number 126401-02-3. This compound is a crucial building block in organic synthesis, particularly for the preparation of peptides and modified amino acids with high precision and minimal side reactions. It is primarily needed by pharmaceutical research organizations, biotechnology companies, and fine chemical manufacturers engaged in advanced drug discovery and development.

Application

• Peptide Synthesis: Serves as a key protected intermediate in solid-phase and solution-phase peptide synthesis (SPPS).
• Pharmaceutical Intermediates: Used in the research and development of novel therapeutic peptides and peptidomimetics.
• Bioconjugation: Acts as a linker or spacer molecule in the creation of antibody-drug conjugates (ADCs) and other bioconjugates.
• Chemical Biology Probes: Employed in the synthesis of labeled amino acids and probes for studying protein function and interactions.
• Material Science: Potential use in the synthesis of specialized polymers and biomaterials.

Basic Information

Item	Detail
Product Name	Norleucine, n-[(Phenylmethoxy)Carbonyl]-, Phenylmethyl Ester
CAS No.	126401-02-3
Molecular Formula	C21H25NO4
Molecular Weight	355.43 g/mol
Synonyms	Nα-Cbz-Norleucine Benzyl Ester; Benzyl N-[(Benzyloxy)carbonyl]-L-norleucinate; (S)-Benzyl 2-((((Benzyloxy)carbonyl)amino)hexanoate; Cbz-Nle-OBzl; Z-Norleucine-OBzl; N-Carbobenzoxy-L-norleucine Benzyl Ester; Nα-Carbobenzyloxy-L-norleucine Benzyl Ester
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide comprehensive analytical data including HPLC purity, chiral purity, and identity confirmation. Certificates of Analysis (COA) are available upon request, detailing batch-specific results for all critical parameters to support your R&D and cGMP manufacturing needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.