Description

3,3-Difluoro-1,5-Pentanediol is a valuable fluorinated diol building block characterized by its two hydroxyl groups separated by a difluoromethylene unit. This unique structure makes it a critical intermediate for introducing fluorine atoms into target molecules, enhancing their metabolic stability, lipophilicity, and binding affinity. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing fluorinated active pharmaceutical ingredients (APIs), prodrugs, and diagnostic agents.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides where fluorine substitution improves efficacy and environmental profile.
• Polymer & Material Science: Serves as a monomer or cross-linker for creating specialty fluorinated polyesters, polyurethanes, and coatings with enhanced chemical resistance and surface properties.
• Liquid Crystal & OLED Materials: A precursor for fluorinated components in electronic display materials, improving dielectric anisotropy and stability.
• Organic Synthesis & Catalysis: Versatile reagent for constructing complex fluorinated molecules in medicinal chemistry and catalyst ligand development.
• Bioconjugation & Linker Chemistry: The diol functionality allows for derivatization to create cleavable linkers or spacers in bioconjugates and probe molecules.

Basic Information

Product Name	3,3-Difluoro-1,5-Pentanediol
CAS No.	126300-39-8
Molecular Formula	C5H10F2O2
Molecular Weight	140.13 g/mol
Synonyms	3,3-Difluoropentane-1,5-diol; 1,5-Pentanediol, 3,3-difluoro-; 3,3-Difluoro-1,5-dihydroxypentane; 3,3-Difluoropentamethylene Glycol; DFPD; 3,3-Difluoropentanediol; 3,3-Difluoro-pentane-1,5-diol
EINECS	Contact for details

Quality Control

Every batch of 3,3-Difluoro-1,5-Pentanediol is produced under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and Karl Fischer titration to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed batch-specific data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive). Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Assay (HPLC/GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.